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[Estrogens and male sexuality: efficiency of antiestrogens in case of hypothalamic hypogonadism and late onset hypogonadism].
[aromatase deficiency]
Estrogen
treatment
in
eugonadal
men
diminishes
libido
,
whereas
libido
is
preserved
by
estrogens
in
orchidectomized
transsexuals
as
well
as
in
cases
of
aromatase
deficiency
.
Hypothalamic
hypogonadism
can
be
caused
by
stress
,
depression
,
anorexia
or
excessive
exercise
.
It
may
result
in
erectile
dysfunction
and
decreased
libido
.
A
7
day
trial
of
clomiphen
(
25
mg
/
day
)
can
be
used
to
test
the
responsiveness
of
the
axis
and
may
be
continued
for
up
to
6
months
as
a
means
to
stimulation
endogenous
LH
and
testosterone
secretion
.
Other
antiestrogens
such
as
raloxifen
or
anastrazol
may
have
similar
effects
in
obese
men
and
in
aging
men
with
late
onset
hypogonadism
(
LOH
)
.
Diseases
Validation
Diseases presenting
"stress"
symptom
aromatase deficiency
cushing syndrome
phenylketonuria
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