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[Periodically leaking capillaries].
[systemic capillary leak syndrome]
The
systemic
capillary
leak
syndrome
(
Clarkson
's
syndrome
)
is
a
rare
idiopathic
disorder
,
characterized
by
recurrent
episodes
of
hypovolaemic
shock
,
haemoconcentration
and
hypoalbuminaemia
due
to
a
sudden
shift
of
fluid
and
macromolecules
from
the
intravascular
to
the
interstitial
space
.
A
young
man
is
presented
in
whom
recurrent
attacks
of
hypotension
and
diffuse
swelling
were
initially
attributed
to
staphylococcal
toxic
shock
syndrome
.
With
the
additional
finding
of
a
monoclonal
gammopathy
,
the
diagnosis
of
systemic
capillary
leak
syndrome
was
made
.
Recognition
of
this
syndrome
is
important
,
as
prophylactic
treatment
with
terbutaline
and
theophylline
may
be
beneficial
in
this
life
threatening
syndrome
.
Diseases
Validation
Diseases presenting
"diffuse swelling were initially attributed to staphylococcal toxic shock syndrome"
symptom
systemic capillary leak syndrome
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