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Our Project
Our Team
[Human immunodeficiency virus-related non-hodgkin lymphoma: a clinical investigation at our hospital].
[primary effusion lymphoma]
We
investigated
8
cases
of
non-
Hodgkin
lymphoma
(
NHL
)
in
human
immunodeficiency
virus
(
HIV
)
seropositive
individuals
who
were
diagnosed
and
treated
at
Osaka
City
General
Hospital
between
April
2002
and
October
2012
.
All
patients
were
men
,
and
the
average
age
at
the
onset
of
NHL
was
46
years
(
range
:
30
-
61
)
.
Histological
types
were
as
follows
:
diffuse
large
B
cell
lymphoma
in
4
patients
,
plasmablastic
lymphoma
in
2
patients
,
primary
effusion
lymphoma
in
1
patient
,
and
Burkitt
lymphoma
in
1
patient
.
In
3
cases
,
HIV
infection
was
identified
before
the
onset
of
NHL
.
Highly
active
anti-retroviral
therapy
(
HAART
)
was
initiated
in
6
cases
,
and
in
4
of
these
,
we
administered
antineoplastic
chemotherapy
.
Three
patients
who
did
not
receive
antineoplastic
chemotherapy
died
within
1
month
of
diagnosis
.
Although
1
of
the
patients
who
received
chemotherapy
achieved
complete
remission
,
this
patient
died
of
BK
virus
nephritis
.
The
remaining
3
patients
achieved
complete
remission
and
are
currently
alive
after
6
to
9
months
.
We
believe
that
the
combination
of
antineoplastic
chemotherapy
with
HAART
will
lead
to
prognostic
improvement
in
HIV-seropositive
patients
with
NHL
.
Diseases
Validation
Diseases presenting
"burkitt lymphoma"
symptom
hodgkin lymphoma, classical
primary effusion lymphoma
waldenström macroglobulinemia
This symptom has already been validated