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Pleomorphic liposarcoma: A cytologic study of five cases.
[pleomorphic liposarcoma]
Pleomorphic
liposarcoma
represents
one
of
the
rarest
variants
of
liposarcoma
.
It
has
a
poor
prognosis
and
unlike
other
variants
of
liposarcoma
,
lacks
a
molecular
or
genetic
signature
.
Histologic
studies
of
pleomorphic
liposarcoma
have
defined
this
lesion
as
a
high
grade
sarcoma
,
which
contains
a
variable
number
of
lipoblasts
.
We
describe
the
cytologic
features
of
five
cases
of
pleomorphic
liposarcoma
,
all
of
which
had
histologic
confirmation
.
We
consistently
identified
numerous
lipoblasts
as
well
as
micro
and
macrovesicular
fat
vacuoles
in
the
background
of
cellular
,
pleomorphic
sarcomatoid
neoplasms
.
The
appearance
of
the
aspirates
differs
substantially
form
other
variants
of
liposarcoma
.
Diagn
.
Cytopathol
.
2014
.
©
2014
Wiley
Periodicals
,
Inc
.
Diseases
Validation
Diseases presenting
"all of which had histologic confirmation"
symptom
pleomorphic liposarcoma
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