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Effect of the herbal medicine dai-kenchu-to on gastrointestinal motility in patients with megacystis-microcolon-intestinal hypoperistalsis syndrome (MMIHS) and chronic idiopathic intestinal pseudo-obstruction (CIIP): report of two cases.
[megacystis-microcolon-intestinal hypoperistalsis syndrome]
Dai
-kenchu-
to
(
DKT
)
,
a
traditional
Japanese
herbal
medicine
(
Kampo
medicine
)
,
composed
of
zanthoxylum
fruit
,
ginseng
root
,
dried
ginger
rhizome
and
malt
sugar
,
is
clinically
effective
for
postoperative
ileus
and
chronic
constipation
.
MMIHS
and
CIIP
are
severe
motility
disorder
associated
with
high
morbidity
.
The
aim
of
this
study
was
to
evaluate
the
effect
of
DKT
on
functional
intestinal
obstruction
.
DKT
was
clinically
effective
for
gastrointestinal
motility
in
a
case
with
MMIHS
,
but
not
effective
in
one
with
CIIP
.
MMIHS
and
CIIP
are
speculated
to
have
different
pathogenesis
regarding
gastrointestinal
pseudo-obstruction
based
upon
the
effect
of
this
drug
.
Diseases
Validation
Diseases presenting
"severe motility disorder"
symptom
megacystis-microcolon-intestinal hypoperistalsis syndrome
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