Rare Diseases Symptoms Automatic Extraction

Successful management of bilateral refractory chylothorax after double lung transplantation for lymphangioleiomyomatosis.

[lymphangioleiomyomatosis]

Lymphangioleiomyomatosis (LAM) is a rare disease that leads to airways and lymphatic channels obstruction due to abnormal smooth muscle proliferation. It presents with dyspnea, pneumothorax or chylothorax. Lung transplantation (LT) has emerged as a valuable therapeutic option with limited reports. We report a case of LAM that underwent double LT and complicated by refractory bilateral chylothorax which was managed successfully by povidone-iodine pleurodesis and the addition of sirolimus to the post-transplantation immunosuppressive therapy. The patient has no recurrence with 24 months follow-up.

Diseases presenting "dyspnea" symptom

  • acute rheumatic fever
  • allergic bronchopulmonary aspergillosis
  • carcinoma of the gallbladder
  • congenital diaphragmatic hernia
  • cushing syndrome
  • cutaneous mastocytosis
  • dedifferentiated liposarcoma
  • erdheim-chester disease
  • esophageal carcinoma
  • fabry disease
  • familial mediterranean fever
  • inclusion body myositis
  • liposarcoma
  • lymphangioleiomyomatosis
  • neuralgic amyotrophy
  • pleomorphic liposarcoma
  • primary effusion lymphoma
  • scrub typhus
  • systemic capillary leak syndrome
  • thoracic outlet syndrome
  • well-differentiated liposarcoma

This symptom has already been validated