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Prevalence and risk factors for allergic bronchopulmonary aspergillosis in Indian children with cystic fibrosis.
[allergic bronchopulmonary aspergillosis]
Allergic
bronchopulmonary
aspergillosis
(
ABPA
)
is
a
common
complication
in
patients
with
cystic
fibrosis
.
This
cross-sectional
study
was
planned
to
determine
the
prevalence
and
risk
factors
for
ABPA
in
Indian
children
with
cystic
fibrosis
.
Clinical
evaluation
,
spirometry
,
chest
radiograph
,
sputum
,
total
IgE
,
specific
IgE
for
Aspergillus
fumigatus
,
IgG
precipitins
and
skin
prick
tests
were
done
in
33
CF
patients
.
Prevalence
of
allergic
bronchopulmonary
aspergillosis
was
18
.
2
%
(
95
%
CI
6
.
9
%
-
35
.
4
%
)
:
allergic
bronchopulmonary
aspergillosis
was
higher
in
patients
with
low
cystic
fibrosis
score
,
age
>
12
years
,
atopy
,
and
eosinophilia
.
Prevalence
of
ABPA
is
higher
in
Indian
children
with
cystic
fibrosis
.
Diseases
Validation
Diseases presenting
"low cystic fibrosis score"
symptom
allergic bronchopulmonary aspergillosis
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