Rare Diseases Symptoms Automatic Extraction
Home
A random Abstract
Our Project
Our Team
Evaluation of quality of life in complete locked-in syndrome patients.
[locked-in syndrome]
There
are
few
studies
where
quality
of
life
(
QOL
)
and
contributive
factors
are
assessed
in
locked-
in
syndrome
(
LIS
)
patients
with
complete
physical
and
functional
disability
and
dependence
on
caregivers
.
The
study
's
objective
was
evaluation
of
QOL
in
LIS
patients
.
We
have
compared
QOL
in
LIS
patients
with
QOL
in
healthy
controls
(
control
group
)
.
We
have
included
19
LIS
patients
,
most
of
them
with
vascular
etiologies
or
terminal
course
of
ALS
,
and
20
healthy
controls
comparable
with
LIS
patients
for
age
;
none
of
them
was
in
a
caregiving
position
.
Administered
to
patients
and
controls
were
the
McGill
Quality
of
Life
Single
Item
Scale
(
MQOL-SIS
)
Part
A
;
Short
Form
survey
(
SF-
36
)
,
Mental
Component
Summary
(
MCS
)
and
Physical
Component
Summary
(
PCS
)
;
Beck
Depression
Inventory-
II
(
BDI-
II
)
;
and
Toronto
Alexithymia
Scale
(
TAS
)
.
Mean
MQOL-SIS
and
MCS
SF-
36
were
not
significantly
different
between
the
LIS
group
and
healthy
controls
.
PCS
SF-
36
score
was
significantly
higher
in
controls
.
There
were
no
significant
differences
between
the
two
groups
for
TAS
scores
.
Frequency
of
depressive
symptoms
was
significantly
higher
in
LIS
patients
than
in
controls
.
In
our
study
,
QOL
in
LIS
patients
was
not
significantly
altered
compared
to
control
subjects
in
MQOL-SIS
and
in
the
MCS
SF-
36
scale
;
these
results
match
previous
studies
published
in
the
literature
.
Several
factors
may
have
an
impact
on
QOL
in
LIS
patients
,
such
as
family
support
and
patient-computer
communication
devices
;
these
may
have
contributed
to
improve
QOL
in
LIS
patients
in
this
study
.
Diseases
Validation
Diseases presenting
"depression"
symptom
22q11.2 deletion syndrome
achondroplasia
adrenal incidentaloma
adrenomyeloneuropathy
alexander disease
aromatase deficiency
cadasil
child syndrome
classical phenylketonuria
congenital adrenal hyperplasia
congenital toxoplasmosis
cushing syndrome
cutaneous mastocytosis
dracunculiasis
fabry disease
familial hypocalciuric hypercalcemia
gm1 gangliosidosis
hereditary cerebral hemorrhage with amyloidosis
krabbe disease
locked-in syndrome
malignant atrophic papulosis
oligodontia
oral submucous fibrosis
phenylketonuria
sneddon syndrome
triple a syndrome
trochlear dysplasia
von hippel-lindau disease
This symptom has already been validated