Rare Diseases Symptoms Automatic Extraction
Home
A random Abstract
Our Project
Our Team
Evaluation of quality of life in complete locked-in syndrome patients.
[locked-in syndrome]
There
are
few
studies
where
quality
of
life
(
QOL
)
and
contributive
factors
are
assessed
in
locked-
in
syndrome
(
LIS
)
patients
with
complete
physical
and
functional
disability
and
dependence
on
caregivers
.
The
study
's
objective
was
evaluation
of
QOL
in
LIS
patients
.
We
have
compared
QOL
in
LIS
patients
with
QOL
in
healthy
controls
(
control
group
)
.
We
have
included
19
LIS
patients
,
most
of
them
with
vascular
etiologies
or
terminal
course
of
ALS
,
and
20
healthy
controls
comparable
with
LIS
patients
for
age
;
none
of
them
was
in
a
caregiving
position
.
Administered
to
patients
and
controls
were
the
McGill
Quality
of
Life
Single
Item
Scale
(
MQOL-SIS
)
Part
A
;
Short
Form
survey
(
SF-
36
)
,
Mental
Component
Summary
(
MCS
)
and
Physical
Component
Summary
(
PCS
)
;
Beck
Depression
Inventory-
II
(
BDI-
II
)
;
and
Toronto
Alexithymia
Scale
(
TAS
)
.
Mean
MQOL-SIS
and
MCS
SF-
36
were
not
significantly
different
between
the
LIS
group
and
healthy
controls
.
PCS
SF-
36
score
was
significantly
higher
in
controls
.
There
were
no
significant
differences
between
the
two
groups
for
TAS
scores
.
Frequency
of
depressive
symptoms
was
significantly
higher
in
LIS
patients
than
in
controls
.
In
our
study
,
QOL
in
LIS
patients
was
not
significantly
altered
compared
to
control
subjects
in
MQOL-SIS
and
in
the
MCS
SF-
36
scale
;
these
results
match
previous
studies
published
in
the
literature
.
Several
factors
may
have
an
impact
on
QOL
in
LIS
patients
,
such
as
family
support
and
patient-computer
communication
devices
;
these
may
have
contributed
to
improve
QOL
in
LIS
patients
in
this
study
.
Diseases
Validation
Diseases presenting
"vascular etiologies"
symptom
locked-in syndrome
You can validate or delete this automatically detected symptom
Validate the Symptom
Delete the Symptom