Improvement of nonbullous congenital ichthyosiform erythroderma following functional endoscopic sinus surgery.

[lamellar ichthyosis]

We report the case of a child with congenital nonbullous ichthyosiform erythroderma on long -term isotretinoin who developed progressively worsening ichthyosis along with recurrent bouts of sinusitis . Endoscopic sinus surgery revealed osteophytes , most likely an isotretinoin-related adverse event , and post operatively the patient 's sinus disease and skin disease both dramatically improved . This case represents the first report , to our knowledge , of ichthyosis improving after endoscopic sinus surgery .