Rare Diseases Symptoms Automatic Extraction
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Harlequin ichthyosis in a HanWoo calf.
[harlequin ichthyosis]
Ichthyosis
(
fish
scale
disease
)
is
a
rare
hereditary
disease
and
characterized
by
excessive
cutaneous
scale
formation
.
A
male
HanWoo
calf
born
by
natural
service
was
found
with
fissures
and
thickened
,
scaly
,
cutaneous
plates
covering
over
90
%
of
its
body
.
Histopathological
feature
was
excess
compact
orthokeratotic
hyperkeratosis
involving
surface
of
the
epidermis
and
follicular
epithelia
.
The
calf
had
small
malformed
ears
,
ectropion
,
eclabium
and
an
abnormal
nose
.
Gross
and
histopathologic
findings
in
calf
were
consistent
with
those
of
harlequin
ichthyosis
,
and
it
was
the
first
observed
harlequin
ichthyosis
in
HanWoo
cattle
.