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Prevalence of periodontal disease in patients with Familial Mediterranean Fever: a cohort study from central Turkey.
[familial mediterranean fever]
The
aim
of
this
study
was
to
compare
the
periodontal
status
in
patients
with
Familial
Mediterranean
Fever
(
FMF
)
and
in
those
without
this
disease
.
84
subjects
clinically
diagnosed
with
FMF
and
75
systemically
healthy
controls
,
matched
by
age
and
gender
,
were
recruited
.
All
FMF
patients
were
on
a
regular
daily
colchicine
treatment
and
during
attack-free
periods
.
Gingival
Index
(
GI
)
,
Plaque
Index
(
PI
)
,
probing
pocket
depth
(
PD
)
,
and
clinical
attachment
level
(
CAL
)
were
measured
in
all
subjects
.
To
evaluate
periodontal
disease
further
,
patients
were
stratified
into
fi
ve
groups
.
Education
information
and
smoking
habits
were
recorded
.
The
FMF
patients
and
healthy
controls
were
comparable
for
age
,
gender
,
and
smoking
status
(
P
>
.
05
)
.
The
FMF
patients
had
significantly
higher
PI
and
GI
values
and
lower
PD
and
CAL
values
than
those
of
the
control
group
(
P
<
.
05
)
.
However
,
there
was
no
significant
difference
among
all
groups
in
terms
of
periodontal
disease
severity
(
P
>
.
05
)
.
In
the
FMF
-
severe
periodontitis
group
,
higher
PI
and
GI
values
were
seen
(
P
<
.
05
)
.
However
,
there
was
no
significant
difference
between
the
FMF
-
severe
periodontitis
group
and
the
controls
with
severe
periodontitis
regarding
the
PD
and
CAL
values
(
P
>
.
05
)
.
Patients
with
FMF
using
colchicine
did
not
manifest
higher
attachment
loss
compared
to
age-
and
sex-matched
systemically
healthy
controls
.
Diseases
Validation
Diseases presenting
"fever"
symptom
22q11.2 deletion syndrome
acute rheumatic fever
alexander disease
allergic bronchopulmonary aspergillosis
canavan disease
carcinoma of the gallbladder
child syndrome
congenital toxoplasmosis
cushing syndrome
cystinuria
dracunculiasis
erdheim-chester disease
esophageal adenocarcinoma
esophageal carcinoma
familial mediterranean fever
focal myositis
hodgkin lymphoma, classical
lamellar ichthyosis
legionellosis
locked-in syndrome
malignant atrophic papulosis
neonatal adrenoleukodystrophy
neuralgic amyotrophy
oculocutaneous albinism
papillon-lefèvre syndrome
pyomyositis
pyruvate dehydrogenase deficiency
scrub typhus
severe combined immunodeficiency
sneddon syndrome
systemic capillary leak syndrome
triple a syndrome
typhoid
waldenström macroglobulinemia
wolf-hirschhorn syndrome
This symptom has already been validated