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Streptomyces infection in Cushing syndrome: A case report and literature review.
[cushing syndrome]
Streptomyces
are
saprophytic
soil
organisms
rarely
known
to
cause
invasive
infections
.
Streptomyces
is
the
largest
genus
,
producing
antibacterial
,
antifungal
and
antiparasitic
drugs
.
The
case
was
a
24
-
year
-old
man
,
admitted
for
sudden
dyspnea
,
fever
and
sputum
and
decreased
sound
in
the
left
lung
.
The
chest
X-
ray
showed
hydropneumothorax
.
After
chest
tube
insertion
,
lung
expansion
did
not
happen
.
Pleural
effusion
was
exudative
with
gram-
positive
bacillus
and
Streptomyces
in
culture
.
Owing
to
symptoms
of
Cushing
in
history
,
examination
and
laboratory
work-up
for
Cushing
was
done
and
finally
he
underwent
bilateral
adrenalectomy
.
The
patient
was
on
antibiotic
broad
spectrum
antibiotic
and
then
was
changed
to
antibiotic
as
organism
was
sensitive
to
and
discharged
with
clarithromycin
for
6
months
.
Streptomyces
happens
in
immunodeficient
patient
.
Diagnosis
is
based
on
culture
and
contamination
was
ruled
out
.
Treatment
period
is
longer
for
patients
owing
to
slow
growing
nature
.