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Lymphoepithelioma-like esophageal carcinoma with macroscopic reduction.
[esophageal carcinoma]
Esophageal
lymphoepithelioma-like
carcinoma
(
LELC
)
is
extremely
rare
.
We
report
the
first
case
of
esophageal
LELC
showing
macroscopic
reduction
.
A
67
-
year
-old
male
presented
with
dysphagia
and
,
by
endoscopic
examination
,
was
found
to
have
a
significantly
raised
tumor
of
10
mm
in
diameter
in
the
thoracic
esophagus
.
The
biopsied
material
showed
esophageal
cancer
.
We
performed
endoscopic
submucosal
dissection
.
However
,
the
tumor
became
flattened
,
similar
to
a
scar
,
in
only
2
mo
.
Histologically
,
the
carcinoma
cells
had
infiltrated
the
submucosal
layer
.
Prominent
infiltration
of
T
lymphoid
cells
that
stained
positive
for
CD
8
was
observed
around
the
carcinoma
cells
.
Therefore
,
this
lesion
was
considered
to
be
an
LELC
with
poorly
differentiated
squamous
cells
.
Because
the
margin
was
positive
,
an
esophagectomy
was
performed
.
Carcinoma
cells
were
detected
in
the
neck
in
one
lymph
node
.
The
staging
was
T
1
N
0
M
1
b
.
However
,
the
patient
has
been
well
,
without
adjuvant
therapy
or
recurrence
,
for
more
than
5
years
.
Diseases
Validation
Diseases presenting
"first case"
symptom
achondroplasia
adrenal incidentaloma
allergic bronchopulmonary aspergillosis
alpha-thalassemia
aniridia
aromatase deficiency
canavan disease
carcinoma of the gallbladder
child syndrome
cholangiocarcinoma
classical phenylketonuria
coats disease
cohen syndrome
congenital toxoplasmosis
cushing syndrome
cutaneous mastocytosis
dedifferentiated liposarcoma
dentin dysplasia
dracunculiasis
dystrophic epidermolysis bullosa
epidermolysis bullosa simplex
esophageal adenocarcinoma
esophageal carcinoma
fabry disease
familial mediterranean fever
focal myositis
gm1 gangliosidosis
harlequin ichthyosis
hodgkin lymphoma, classical
homocystinuria without methylmalonic aciduria
junctional epidermolysis bullosa
kabuki syndrome
krabbe disease
lamellar ichthyosis
legionellosis
liposarcoma
locked-in syndrome
malignant atrophic papulosis
monosomy 21
neonatal adrenoleukodystrophy
oculocutaneous albinism
omenn syndrome
papillon-lefèvre syndrome
pendred syndrome
pleomorphic liposarcoma
primary effusion lymphoma
primary hyperoxaluria type 1
proteus syndrome
pyomyositis
systemic capillary leak syndrome
thoracic outlet syndrome
von hippel-lindau disease
waldenström macroglobulinemia
well-differentiated liposarcoma
werner syndrome
wolf-hirschhorn syndrome
x-linked adrenoleukodystrophy
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