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Peripheral dentinogenic ghost cell tumor: a case report and review of the literature.
[dentin dysplasia]
Dentinogenic
ghost
cell
tumor
(
DGCT
)
is
a
rare
neoplasm
,
representing
1
.
9
%
to
2
.
1
%
of
all
odontogenic
tumors
.
Few
cases
of
DGCT
have
been
reported
and
only
11
show
no
bone
involvement
.
A
rare
case
of
peripheral
DGCT
is
reported
,
located
in
the
anterior
mandible
of
a
45
-
year
-old
man
.
The
patient
presented
a
slow
painless
growth
in
the
canine
region
of
an
edentulous
mandible
.
Radiographically
,
no
bone
involvement
was
registered
.
The
lesion
was
enucleated
and
microscopically
characterized
by
islands
of
epithelial
cells
showing
ameloblastomalike
features
in
fibrous
tissue
.
Dysplasic
dentin
and
ghost
cells
were
frequently
observed
.
Areas
showing
a
connection
between
tumor
cells
and
the
overlying
mucosa
were
also
identified
.
Immunohistochemical
analysis
demonstrated
positivity
for
pan-cytokeratin
,
cytokeratin-
14
,
and
2
neural
markers
.
Denditric
cells
(
Langerhans
cells
and
melanocytes
)
were
identified
inside
tumoral
islands
.
A
rare
case
of
peripheral
DGCT
is
reported
,
with
immunohistochemical
analysis
and
a
review
of
the
English
literature
.
