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In vivo and in vitro evidence of somatostatin receptors expression in a dedifferentiated retroperitoneal liposarcoma.
[dedifferentiated liposarcoma]
A
62
-
year
-old
patient
presented
with
mildly
elevated
catecholamines
and
an
abdominal
painless
mass
.
Abdominal
CT
revealed
an
18
×
12
cm
tumor
in
the
right
retroperitoneum
with
intense
contrast
enhancement
.
Somatostatin
receptor
scintigraphy
(
SRS
)
showed
pathologic
uptake
by
the
lesion
.
Given
the
suspicion
of
paraganglioma
,
the
patient
was
referred
to
surgery
for
tumor
removal
.
Surprisingly
,
the
histopathological
examination
revealed
a
dedifferentiated
liposarcoma
.
Somatostatin
receptors
of
type
2
were
identified
and
quantified
by
reverse
transcription
polymerase
chain
reaction
.
The
unexpected
presentation
of
our
patient
draws
clinicians
'
attention
when
performing
diagnostic
procedure
for
retroperitoneal
lesions
,
even
though
hormone
secretion
and
positive
SRS
strongly
suggest
paraganglioma
.
Diseases
Validation
Diseases presenting
"the patient was referred to surgery for tumor removal"
symptom
dedifferentiated liposarcoma
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