Rare Diseases Symptoms Automatic Extraction

[Childhood-onset mastocytosis].

[cutaneous mastocytosis]

Mastocytoses are a group of rare diseases characterized, in most cases, by a benign proliferation and accumulation of mast cells in different tissues. In children, mastocytosis affects usually exclusively the skin and differs in many aspects from adult-onset mastocytosis. Except for diffuse cutaneous mastocytosis, which is an uncommon subtype of childhood-onset mastocytosis, involvement of the bone marrow or additional extracutaneous organs is rarely seen in children. The prognosis of childhood-onset mastocytosis is usually very good. Compared to adult patients who most commonly experience chronic-stable or slowly progressive disease, mastocytosis in children is mostly transient and self-limiting. In this review, we present and discuss the subtypes of childhood-onset mastocytosis, recent advances in the understanding of their pathogenesis as well as similarities and differences between adult- and childhood-onset mastocytosis.

Diseases presenting "bone marrow" symptom

  • adrenomyeloneuropathy
  • allergic bronchopulmonary aspergillosis
  • cohen syndrome
  • cushing syndrome
  • cutaneous mastocytosis
  • erdheim-chester disease
  • erythropoietic protoporphyria
  • focal myositis
  • hodgkin lymphoma, classical
  • krabbe disease
  • legionellosis
  • liposarcoma
  • monosomy 21
  • oculocutaneous albinism
  • omenn syndrome
  • papillon-lefèvre syndrome
  • pyomyositis
  • scrub typhus
  • severe combined immunodeficiency
  • systemic capillary leak syndrome
  • waldenström macroglobulinemia
  • werner syndrome
  • wiskott-aldrich syndrome

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