Rare Diseases Symptoms Automatic Extraction

Imatinib mesylate in the treatment of diffuse cutaneous mastocytosis.

[cutaneous mastocytosis]

Diffuse cutaneous mastocytosis is a less common but potentially life-threatening variant of childhood mastocytosis. Here we report 2 children with diffuse cutaneous mastocytosis in whom an activating somatic KIT mutation was detected. Treatment with imatinib, a KIT inhibitor, resulted in resolution of the lesions and were well tolerated by the patients.

Diseases presenting "potentially life-threatening variant" symptom

  • cutaneous mastocytosis

You can validate or delete this automatically detected symptom