Rare Diseases Symptoms Automatic Extraction
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A random Abstract
Our Project
Our Team
Neuropathology of stress.
[cushing syndrome]
Environmental
challenges
are
part
of
daily
life
for
any
individual
.
In
fact
,
stress
appears
to
be
increasingly
present
in
our
modern
,
and
demanding
,
industrialized
society
.
Virtually
every
aspect
of
our
body
and
brain
can
be
influenced
by
stress
and
although
its
effects
are
partly
mediated
by
powerful
corticosteroid
hormones
that
target
the
nervous
system
,
relatively
little
is
known
about
when
,
and
how
,
the
effects
of
stress
shift
from
being
beneficial
and
protective
to
becoming
deleterious
.
Decades
of
stress
research
have
provided
valuable
insights
into
whether
stress
can
directly
induce
dysfunction
and
/
or
pathological
alterations
,
which
elements
of
stress
exposure
are
responsible
,
and
which
structural
substrates
are
involved
.
Using
a
broad
definition
of
pathology
,
we
here
review
the
"
neuropathology
of
stress
"
and
focus
on
structural
consequences
of
stress
exposure
for
different
regions
of
the
rodent
,
primate
and
human
brain
.
We
discuss
cytoarchitectural
,
neuropathological
and
structural
plasticity
measures
as
well
as
more
recent
neuroimaging
techniques
that
allow
direct
monitoring
of
the
spatiotemporal
effects
of
stress
and
the
role
of
different
CNS
structures
in
the
regulation
of
the
hypothalamic
-
pituitary
-
adrenal
axis
in
human
brain
.
We
focus
on
the
hypothalamus
,
hippocampus
,
amygdala
,
nucleus
accumbens
,
prefrontal
and
orbitofrontal
cortex
,
key
brain
regions
that
not
only
modulate
emotions
and
cognition
but
also
the
response
to
stress
itself
,
and
discuss
disorders
like
depression
,
post-traumatic
stress
disorder
,
Cushing
syndrome
and
dementia
.
Diseases
Validation
Diseases presenting
"depression"
symptom
22q11.2 deletion syndrome
achondroplasia
adrenal incidentaloma
adrenomyeloneuropathy
alexander disease
aromatase deficiency
cadasil
child syndrome
classical phenylketonuria
congenital adrenal hyperplasia
congenital toxoplasmosis
cushing syndrome
cutaneous mastocytosis
dracunculiasis
fabry disease
familial hypocalciuric hypercalcemia
gm1 gangliosidosis
hereditary cerebral hemorrhage with amyloidosis
krabbe disease
locked-in syndrome
malignant atrophic papulosis
oligodontia
oral submucous fibrosis
phenylketonuria
sneddon syndrome
triple a syndrome
trochlear dysplasia
von hippel-lindau disease
This symptom has already been validated