Multiple endocrine neoplasia type IIa associated with Cushing's syndrome.

[cushing syndrome]

Multiple Endocrine Neoplasia type IIa (MEN IIa ) is an autosomal dominant syndrome characterized by pheochromocytoma , medullary thyroid carcinoma and hyperparathyroidism . Pheochromocytoma occurs in approximately 50 % of patients with MEN IIa . This tumor has the capacity to produce ACTH ectopically and manifests as the Cushing syndrome , although it is very rare . We report a 26 -year -old woman patient with severe muscle weakness , skin lesions in extremities , hypertension , and new onset diabetes whose laboratory findings included hypokalemia , metabolic alkalosis , high serum level of cortisol , metanephrine , normetanephrine , calcitonin and bilateral adrenal mass in computed tomography as the first clinical manifestations of an ACTH-secreting pheochromocytoma . In the patients with hypertension , new onset diabetes and hypokalemia , the Cushing syndrome and pheochromocytoma should always be ruled out .

Diseases
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Diseases presenting "and new onset diabetes whose laboratory findings included hypokalemia" symptom

cushing syndrome

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