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Posterior polymorphous corneal dystrophy concomitant to large colloid drusen.
[]
To
describe
the
previously
unreported
concomitance
of
2
uncommon
ocular
conditions
:
posterior
polymorphous
corneal
dystrophy
(
PPCD
)
and
large
colloid
drusen
(
LCD
)
.
A
45
-
year
-old
woman
underwent
a
complete
ophthalmologic
examination
with
slit-lamp
biomicroscopy
and
blue
fundus
autofluorescence
with
spectral-domain
optical
coherence
tomography
,
as
well
as
complete
systemic
examination
and
renal
function
investigation
.
On
slit-lamp
biomicroscopy
,
a
corneal
lesion
located
at
Descemet
membrane
was
observed
in
the
right
eye
.
The
clinical
features
of
deep
posterior
stromal-endothelial
linear
bands
with
vesicles
and
irregular
opacities
of
posterior
corneal
surface
were
consistent
with
the
diagnosis
of
PPCD
.
Fundus
biomicroscopy
and
blue
fundus
autofluorescence
showed
LCD
.
We
report
the
unusual
coexistence
of
PPCD
and
LCD
in
a
young
,
healthy
subject
.
Posterior
polymorphous
corneal
dystrophy
and
LCD
share
morphologic
similarities
and
dysfunctions
of
collagen
architecture
in
the
basement
membrane
layer
,
which
suggests
a
possible
common
pathogenic
pathway
.
