Rare Diseases Symptoms Automatic Extraction
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Acute rheumatic fever and streptococci: the quintessential pathogenic trigger of autoimmunity.
[acute rheumatic fever]
Acute
rheumatic
fever
(
ARF
)
is
a
non-suppurative
complication
of
pharyngeal
infection
with
group
A
streptococcus
.
Signs
and
symptoms
of
ARF
develop
2
to
3
Â
weeks
following
pharyngitis
and
include
arthritis
,
carditis
,
chorea
,
subcutaneous
nodules
,
and
erythema
marginatum
.
In
developing
areas
of
the
world
,
ARF
and
rheumatic
heart
disease
are
estimated
to
affect
nearly
20
million
people
and
remain
leading
causes
of
cardiovascular
death
during
the
first
five
decades
of
life
.
ARF
still
represents
one
of
the
quintessential
examples
of
a
pathogenic
trigger
culminating
in
autoimmune
manifestations
.
In
this
review
,
we
will
focus
on
the
pathogenesis
and
etiology
of
ARF
and
its
complications
,
along
with
diagnostic
and
treatment
approaches
to
both
ameliorate
and
prevent
long
-term
sequelae
of
this
potentially
debilitating
disease
.
Diseases
Validation
Diseases presenting
"fever"
symptom
22q11.2 deletion syndrome
acute rheumatic fever
alexander disease
allergic bronchopulmonary aspergillosis
canavan disease
carcinoma of the gallbladder
child syndrome
congenital toxoplasmosis
cushing syndrome
cystinuria
dracunculiasis
erdheim-chester disease
esophageal adenocarcinoma
esophageal carcinoma
familial mediterranean fever
focal myositis
hodgkin lymphoma, classical
lamellar ichthyosis
legionellosis
locked-in syndrome
malignant atrophic papulosis
neonatal adrenoleukodystrophy
neuralgic amyotrophy
oculocutaneous albinism
papillon-lefèvre syndrome
pyomyositis
pyruvate dehydrogenase deficiency
scrub typhus
severe combined immunodeficiency
sneddon syndrome
systemic capillary leak syndrome
triple a syndrome
typhoid
waldenström macroglobulinemia
wolf-hirschhorn syndrome
This symptom has already been validated