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The lung to thorax transverse area ratio has a linear correlation with the observed to expected lung area to head circumference ratio in fetuses with congenital diaphragmatic hernias.
[congenital diaphragmatic hernia]
The
purpose
of
this
study
was
to
clarify
the
relationship
between
the
lung
to
thorax
transverse
area
ratio
(
L
/
T
ratio
)
and
the
observed
to
expected
lung
area
to
head
circumference
ratio
(
O
/
E
LHR
)
,
based
on
the
results
of
a
nationwide
Japanese
survey
conducted
in
2011
,
and
to
evaluate
the
compatibility
of
these
prognostic
predictors
of
fetal
CDH
.
T
wo
hundred
and
forty-
two
prenatally
diagnosed
isolated
CDH
patients
born
between
2006
and
2010
were
included
in
the
present
analysis
.
A
regression
analysis
was
conducted
to
investigate
the
relationship
between
the
L
/
T
ratio
and
the
O
/
E
LHR
based
on
191
simultaneous
measurements
of
these
parameters
in
120
patients
.
The
linear
regression
equation
between
the
L
/
T
ratio
and
the
O
/
E
LHR
was
:
L
/
T
ratio
=
0
.
0233
+
(
0
.
00222
×
O
/
E
LHR
)
,
(
R
=
0
.
847
,
p
<
0
.
0001
)
.
According
to
this
equation
,
25
%
of
the
O
/
E
LHR
,
the
cut-off
value
used
in
the
fetal
intervention
for
CDH
,
was
equivalent
to
an
L
/
T
ratio
of
0
.
08
,
a
commonly
accepted
cut-off
value
for
identifying
the
most
severe
cases
of
fetal
CDH
.
As
there
is
a
positive
correlation
between
the
L
/
T
ratio
and
the
O
/
E
LHR
,
these
two
parameters
proved
to
be
used
interchangeably
according
to
the
linear
regression
equation
.
