Intraductal papillary neoplasm of the bile duct developing in a patient with primary sclerosing cholangitis: A case report.

[cholangiocarcinoma]

We report a case of intraductal papillary neoplasm of the bile duct (IPNB ) that developed in a patient with primary sclerosing cholangitis . A 46 -year -old woman was admitted to our hospital with obstructive jaundice . The liver function tests demonstrated increased serum liver enzyme levels . Computed tomography showed dilatation of the intrahepatic bile ducts . Abdominal ultrasonography revealed a highly echoic protruding lesion in the posterior bile duct near the right lobe of the liver . The lesion was suspected to be IPNB , but we were unable to confirm whether it was a carcinoma . A right hepatectomy was performed , and this showed that the dilated bile duct was filled with mucin and contained several yellowish papillary tumors . Histologically , the neoplastic biliary epithelium showed papillary growth in the dilated lumen . The tumor was diagnosed as IPNB , high -grade intraepithelial neoplasia secreting abundant mucin . No recurrence has been detected 3 years after surgery .