Rare Diseases Symptoms Automatic Extraction
Home
A random Abstract
Our Project
Our Team
Association of mustard oil as cooking media with carcinoma of the gallbladder.
[carcinoma of the gallbladder]
Carcinoma
of
the
gallbladder
(
CaGB
)
is
a
common
health
problem
in
Northern
India
.
Exact
causative
factors
are
still
obscure
.
Dietary
habits
are
also
known
to
be
a
major
factor
in
the
gallbladder
carcinogenesis
.
Mustard
oil
is
mostly
used
as
cooking
media
,
which
is
adulterated
by
sanguinarine
,
diethylnitrosamine
and
repeated
frying
.
We
tried
to
find
out
the
association
of
mustard
oil
as
cooking
media
with
CaGB
.
Twenty
patients
each
of
CaGB
(
group
I
)
and
cholelithiasis
(
group
II
)
were
included
in
the
study
.
Sanguinarine
and
diethylnitrosamine
(
DEN
)
were
extracted
from
the
tissue
and
blood
samples
from
both
groups
.
Mean
and
standard
error
of
mean
of
the
concentration
of
the
sanguinarine
and
DEN
were
calculated
.
Mann-
Whitney
U
test
was
applied
to
test
the
level
of
significance
between
the
two
groups
.
The
mean
concentration
of
tissue
sanguinarine
in
both
groups
(
I
and
II
)
was
195
.
18
ng
/
mg
and
24
.
05
ng
/
mg
,
respectively
,
and
the
difference
was
statistically
highly
significant
(
p
<
0
.
001
)
.
The
estimated
concentration
of
blood
sanguinarine
was
230
.
96
ng
/
mL
and
14
.
0
ng
/
mL
in
group
I
and
II
,
respectively
,
and
the
difference
was
statistically
highly
significant
(
p
<
0
.
001
)
.
The
concentration
of
DEN
in
the
tissue
sample
was
38
.
08
ng
/
mg
in
CaGB
and
2
.
51
ng
/
mg
in
cholelithiasis
patient
,
and
these
values
were
statistically
highly
significant
(
p
<
0
.
001
)
.
Similarly
,
blood
DEN
concentration
was
119
.
05
ng
/
mL
and
4
.
22
ng
/
mL
in
group
I
and
II
,
respectively
,
and
the
difference
was
statistically
highly
significant
(
p
<
0
.
001
)
.
There
is
an
increase
in
concentration
of
sanguinarine
and
diethylnitrosamine
in
CaGB
blood
and
tissue
in
comparison
to
the
cholelithiasis
group
suggesting
an
association
with
carcinoma
of
the
gallbladder
.
Diseases
Validation
Diseases presenting
"blood sanguinarine"
symptom
carcinoma of the gallbladder
You can validate or delete this automatically detected symptom
Validate the Symptom
Delete the Symptom