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[Prevalence, physiopathology and processes associated with hypouricemia in a hospitalized population: analysis of 27,987 analytic determinations].
[]
A
prospective
analysis
of
27
,
987
serum
samples
revealed
a
uricemia
less
than
2
.
0
mg
/
dl
in
172
patients
(
prevalence
of
0
.
61
%
)
.
One
hundred
and
six
patients
were
being
treated
with
more
than
one
drug
.
Amongst
the
21
hypouricemic
patients
receiving
only
one
drug
the
more
frequently
associated
drugs
were
beta
-lactamases
,
salicylates
at
high
doses
,
and
carbamazepine
.
Out
of
the
45
hypouricemic
patients
who
were
under
no
treatment
,
there
were
12
cases
of
pregnancies
,
6
had
a
neoplastic
disease
,
2
suffered
chronic
hepatopathy
and
one
presented
hereditary
xanthinuria
.
Out
of
7
non
treated
patients
,
6
were
uric
acid
hypersecretors
and
only
one
was
hyposecretor
.
The
results
indicate
that
hypouricemia
:
a
)
is
usually
associated
with
an
elevated
renal
excretion
of
uric
acid
and
b
)
it
is
frequently
associated
with
the
administration
of
drugs
although
it
can
also
be
included
in
the
context
of
multiple
systemic
disease
.
