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Correlations between F-18 FDG PET/CT and pathological findings in soft tissue lesions.
[well-differentiated liposarcoma]
To
evaluate
the
correlations
between
F-
18
FDG
uptake
imaged
with
PET
/
CT
and
pathological
findings
in
soft
tissue
lesions
.
Fifty
-
four
soft
tissue
lesions
in
47
patients
were
evaluated
.
The
correlations
between
the
degree
of
FDG
uptake
,
pathological
type
and
grade
,
and
MRI
signal
intensity
and
/
or
enhancement
pattern
were
evaluated
.
Tumor
FDG
uptake
was
quantified
by
the
maximum
standardized
uptake
value
(
SUVmax
)
.
Thirty
-
one
lesions
were
malignant
and
twenty-
three
lesions
were
benign
.
The
difference
between
SUVmax
in
the
malignant
and
benign
groups
was
statistically
significant
(
p
<
0
.
001
)
.
Malignant
myxoid
lesions
and
well
differentiated
liposarcoma
showed
low
FDG
uptake
.
Benign
neurogenic
lesions
showed
low
FDG
uptake
while
malignant
neurogenic
tumors
showed
high
FDG
uptake
,
and
the
difference
between
SUVmax
in
the
benign
and
malignant
lesions
was
statistically
significant
(
p
<
0
.
001
)
.
In
a
neurofibromatosis
type
-
1
patient
who
had
multiple
neurogenic
tumors
,
FDG-PET
/
CT
could
distinguish
malignant
peripheral
nerve
sheath
tumors
from
other
benign
lesions
with
similar
MRI
findings
.
FDG-PET
/
CT
is
useful
for
differentiating
malignant
from
benign
soft
tissue
lesions
,
but
malignant
soft
tissue
lesions
may
show
various
patterns
on
FDG-PET
,
and
MRI
may
be
helpful
for
a
differential
diagnosis
.
Diseases
Validation
Diseases presenting
"malignant lesions"
symptom
adrenal incidentaloma
cowden syndrome
focal myositis
liposarcoma
neuralgic amyotrophy
oral submucous fibrosis
thoracic outlet syndrome
von hippel-lindau disease
well-differentiated liposarcoma
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