FDG PET/CT findings in a rare case of giant fibrovascular polyp of the esophagus harboring atypical lipomatous tumor/well-differentiated liposarcoma.

[well-differentiated liposarcoma]

A 70 -year -old man with a history of chronic lymphocytic leukemia (CLL ) underwent FDG PET /CT scan , which revealed a large polypoid soft tissue lesion in the esophagus with peripheral FDG avidity . An endoscopic biopsy revealed inflammatory changes with scattered CLL cells . The final histopathology demonstrated an 18 -cm long and 4 -cm wide giant fibrovascular polyp that was removed in 2 pieces . The polyp was composed of atypical adipose tissue with scattered giant cells and spindle-shaped cells as well as foci of CLL . Mouse double minute 2 homolog amplification was noted by fluorescence in situ hybridization diffusely in the giant polyp consistent with well-differentiated liposarcoma in a giant fibrovascular polyp .