Rare Diseases Symptoms Automatic Extraction

[Waldenström macroglobulinemia].

[waldenström macroglobulinemia]

Waldenström macroglobulinemia is a rare lymphoproliferative disease of B-cell origin.These tumorous B-cells produce monoclonal IgM type protein. Diagnosis is based on the detection of lymphoplasmacytic invasion of the bone marrow and serum electrophoresis. Clinical symptoms such as anemia, hyperviscosity and neuropathy are the commom consequences of bone marrow infiltration and serum monoclonal IgM protein. Former use of alkylating agents are replaced by purine analogues, rituximab and bortezomib. Additional clinical data have also accumulated regarding autologous and allogenous stem-cell transplantation. The authors present their own clinical experience and give a detailed review of current therapeutic approaches. Orv. Hetil., 154(50), 1970-1974.

Diseases presenting "bone marrow" symptom

  • adrenomyeloneuropathy
  • allergic bronchopulmonary aspergillosis
  • cohen syndrome
  • cushing syndrome
  • cutaneous mastocytosis
  • erdheim-chester disease
  • erythropoietic protoporphyria
  • focal myositis
  • hodgkin lymphoma, classical
  • krabbe disease
  • legionellosis
  • liposarcoma
  • monosomy 21
  • oculocutaneous albinism
  • omenn syndrome
  • papillon-lefèvre syndrome
  • pyomyositis
  • scrub typhus
  • severe combined immunodeficiency
  • systemic capillary leak syndrome
  • waldenström macroglobulinemia
  • werner syndrome
  • wiskott-aldrich syndrome

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