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[Clinical study on patients with renal-cell carcinoma accompanied with von hippel lindau disease treated with radiofrequency ablation].
[von hippel-lindau disease]
We
report
12
renal
cell
carcinomas
in
6
patients
with
Von
Hippel-
Lindau
(
VHL
)
disease
treated
with
radiofrequency
ablation
(
RFA
)
.
The
mean
age
of
the
patients
was
46
(
range
38
-
53
)
years
(
male
:
4
,
female
:
2
)
.
Computed
tomography
(
CT
)
-
guided
transcutaneous
RFA
was
performed
under
conscious
sedation
with
local
anesthetics
.
The
mean
size
of
the
tumors
was
2
.
4
(
range
0
.
7
-
8
.
1
)
cm
.
Nine
of
the
12
tumors
(
75
%
)
were
locally
well
controlled
.
However
,
3
tumors
in
2
patients
developed
visceral
metastases
after
RFA
.
While
minimal
flank
pain
,
nausea
,
perinephritic
hematoma
and
lumbago
were
observed
,
there
was
no
major
complication
during
or
after
the
procedure
.
The
therapy
with
CT
-guided
transcutaneous
RFA
is
efficient
and
minimal
invasive
for
renal
cell
carcinoma
in
patients
with
VHL
,
leading
to
preservation
of
renal
function
.
Diseases
Validation
Diseases presenting
"nausea"
symptom
cadasil
carcinoma of the gallbladder
cholangiocarcinoma
cutaneous mastocytosis
dedifferentiated liposarcoma
erythropoietic protoporphyria
homocystinuria without methylmalonic aciduria
oral submucous fibrosis
proteus syndrome
scrub typhus
systemic capillary leak syndrome
typhoid
von hippel-lindau disease
This symptom has already been validated