Rare Diseases Symptoms Automatic Extraction

Solid variant of papillary cystadenoma of the epididymis.

[von hippel-lindau disease]

Papillary cystadenoma of the epididymis (PCE) is a rare epididymal neoplasm characterized by small and large cystic spaces filled with predominantly papillary projections lined by clear cells. Bilateral PCE has a strong association with von Hippel-Lindau disease (VHLD) (1) . Previous studies have shown that PCE has an immunohistochemical staining profile identical to clear cell papillary renal cell carcinoma (RCC) (2) , with the only difference being primary tumor location. Herein, we describe a rare case of PCE with an exclusively solid growth pattern and emphasize the importance of ancillary immunohistochemistry in establishing the correct diagnosis. This article is protected by copyright. All rights reserved.