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A statistical shape model of trochlear dysplasia of the knee.
[trochlear dysplasia]
Trochlear
dysplasia
is
known
as
the
primary
predisposing
factor
for
patellar
dislocation
.
Current
methods
to
describe
trochlear
dysplasia
are
mainly
qualitative
or
based
on
a
limited
number
of
discrete
measurements
.
The
purpose
of
this
study
is
to
apply
statistical
shape
analysis
to
take
the
full
geometrical
complexity
of
trochlear
dysplasia
into
account
.
Statistical
shape
analysis
was
applied
to
20
normal
and
20
trochlear
dysplastic
distal
femur
models
,
including
the
cartilage
.
This
study
showed
that
the
trochlea
was
anteriorized
,
proximalized
and
lateralized
and
that
the
mediolateral
width
and
the
notch
width
were
decreased
in
the
trochlear
dysplastic
femur
compared
to
the
normal
femur
.
The
first
three
principal
components
of
the
trochlear
dysplastic
femurs
,
accounting
for
79
.
7
%
of
the
total
variation
,
were
size
,
sulcus
angle
and
notch
width
.
Automated
classification
of
the
trochlear
dysplastic
and
normal
femora
achieved
a
sensitivity
of
85
%
and
a
specificity
of
95
%
.
This
study
shows
that
shape
analysis
is
an
outstanding
method
to
visualise
the
location
and
magnitude
of
shape
abnormalities
.
Improvement
of
automated
classification
and
subtyping
within
the
trochlear
dysplastic
group
are
expected
when
larger
training
sets
are
used
.
Classification
of
trochlear
dysplasia
,
especially
borderline
cases
may
be
facilitated
by
automated
classification
.
Furthermore
,
the
identification
of
a
decreased
notch
width
in
association
with
an
increased
sulcus
angle
can
also
contribute
to
the
diagnosis
of
trochlear
dysplasia
.
Diseases
Validation
Diseases presenting
"limited number"
symptom
22q11.2 deletion syndrome
achondroplasia
cholangiocarcinoma
congenital diaphragmatic hernia
dedifferentiated liposarcoma
dentinogenesis imperfecta
epidermolysis bullosa simplex
erythropoietic protoporphyria
liposarcoma
neonatal adrenoleukodystrophy
pleomorphic liposarcoma
primary hyperoxaluria type 1
proteus syndrome
trochlear dysplasia
well-differentiated liposarcoma
werner syndrome
wiskott-aldrich syndrome
x-linked adrenoleukodystrophy
zellweger syndrome
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