Rare Diseases Symptoms Automatic Extraction

Idiopathic systemic capillary leak syndrome (SCLS): case report and systematic review of cases reported in the last 16 years.

[systemic capillary leak syndrome]

'Idiopathic systemic capillary leak syndrome (SCLS), or Clarkson's disease is an unusual entity first described 45 years ago. It presents with recurrent episodes of shock due to leakage of the plasma, which is reflected by accompanying hemo-concentration, hypo-albuminemia and edema. We report the case of a young man with multiple episodes of shock with generalized edema and pleural effusion. An initial diagnosis of sepsis was made, but the lack of fever and absence of a demonstrable organism or source led to a revision of diagnosis to SLCS. The last review of this syndrome which analyzed 24 cases was published in 1990. Since then, 75 more cases have been reported. This article reviews these cases.

Diseases presenting "sepsis" symptom

  • acute rheumatic fever
  • carcinoma of the gallbladder
  • congenital diaphragmatic hernia
  • cushing syndrome
  • cystinuria
  • dystrophic epidermolysis bullosa
  • epidermolysis bullosa simplex
  • focal myositis
  • harlequin ichthyosis
  • heparin-induced thrombocytopenia
  • hirschsprung disease
  • homocystinuria without methylmalonic aciduria
  • inclusion body myositis
  • junctional epidermolysis bullosa
  • kindler syndrome
  • lamellar ichthyosis
  • locked-in syndrome
  • malignant atrophic papulosis
  • megacystis-microcolon-intestinal hypoperistalsis syndrome
  • monosomy 21
  • primary effusion lymphoma
  • primary hyperoxaluria type 1
  • pyomyositis
  • scrub typhus
  • systemic capillary leak syndrome
  • typhoid

This symptom has already been validated