Rare Diseases Symptoms Automatic Extraction
Home
A random Abstract
Our Project
Our Team
[Antiphospholipid antibodies in a female patient with the Sneddon syndrome].
[sneddon syndrome]
Sneddon
was
the
first
one
to
describe
the
association
of
cerebrovascular
insult
(
CVI
)
and
skin
changes
by
livedo
reticularis
type
.
Angiography
of
this
patient
revealed
normal
brain
blood
vessels
,
occlusive
changes
or
the
changes
similar
to
those
in
moya-moya
disease
.
Computed
tomography
(
CT
)
of
the
brain
most
frequently
revealed
ischemic
lesions
and
/
or
diffuse
atrophy
of
the
brain
,
although
the
normal
finding
was
also
possible
.
Considering
the
frequent
finding
of
the
increased
titer
of
anticardiolipin
antibodies
(
ACA
)
in
those
patients
,
those
antibodies
could
be
the
most
important
in
the
pathogenesis
of
Sneddon
's
syndrome
.
A
case
of
female
patient
,
aged
66
years
,
with
livedo
reticularis
and
recurrent
CVI
was
presented
in
this
study
.
By
panangiography
were
revealed
normal
blood
vessels
of
the
brain
,
by
scintigraphy
two
ischemic
lesions
and
by
CT
ischemic
lesions
with
pronounced
cortical
and
subcortical
reductive
changes
.
In
laboratory
findings
were
observed
increased
immunocomplexes
and
the
presence
of
lupus-like
anticoagulants
,
increased
ACA
titer
,
the
increase
in
fibrinogen
value
associated
with
increased
ESR
.
The
result
of
bone
marrow
examination
was
normal
,
while
the
borreliosis
test
was
negative
.
Vasculitis
was
excluded
by
skin
biopsy
.
Solid
improvement
was
noticed
after
the
immunosuppresive
therapy
was
administered
,
but
in
the
last
disease
exacerbation
with
new
CVI
,
the
outcome
was
lethal
3
years
since
the
disease
onset
.
Diseases
Validation
Diseases presenting
"female patient"
symptom
achondroplasia
adrenal incidentaloma
alexander disease
aniridia
aromatase deficiency
benign recurrent intrahepatic cholestasis
carcinoma of the gallbladder
coats disease
cohen syndrome
cowden syndrome
cushing syndrome
cutaneous mastocytosis
dedifferentiated liposarcoma
dentinogenesis imperfecta
epidermolysis bullosa simplex
esophageal squamous cell carcinoma
fabry disease
holt-oram syndrome
hydrocephalus with stenosis of the aqueduct of sylvius
kallmann syndrome
kindler syndrome
krabbe disease
lamellar ichthyosis
liposarcoma
lymphangioleiomyomatosis
malignant atrophic papulosis
monosomy 21
neuralgic amyotrophy
oculocutaneous albinism
oligodontia
oral submucous fibrosis
papillon-lefèvre syndrome
pendred syndrome
primary hyperoxaluria type 1
proteus syndrome
pyomyositis
pyruvate dehydrogenase deficiency
sneddon syndrome
systemic capillary leak syndrome
thoracic outlet syndrome
triple a syndrome
von hippel-lindau disease
waldenström macroglobulinemia
x-linked adrenoleukodystrophy
You can validate or delete this automatically detected symptom
Validate the Symptom
Delete the Symptom