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[Cerebrovascular diseases in patients aged 15 to 40 years: neuropathological findings in 47 cases].
[sneddon syndrome]
Cerebrovascular
diseases
in
patients
between
15
and
40
years
old
are
not
a
frequent
subject
in
Latin-
American
literature
,
especially
when
focusing
on
neuropathology
.
We
analyzed
47
brains
from
necropsies
performed
from
1987
to
1997
and
selected
on
a
basis
of
age
and
the
presence
of
vascular
pathology
.
From
the
47
analyzed
brains
,
26
belonged
to
females
(
55
.
3
%
)
.
When
distributed
among
age
groups
,
12
.
8
%
(
n
=
6
)
affected
patients
from
15
to
20
yo
,
51
,
1
%
(
n
=
24
)
from
21
to
30
yo
,
36
,
2
%
(
n
=
17
)
from
31
to
40
yo
.
The
underlying
diseases
were
:
cardiac
and
haemathologic
(
19
.
2
%
)
,
pregnancy
complications
(
12
.
76
%
)
,
infections
,
diseases
of
blood
vessels
and
neurological
(
10
.
1
%
each
)
amongst
others
.
The
neuropathological
abnormalities
included
cerebral
and
/
or
cerebellar
herniation
(
16
%
)
,
cerebral
edema
(
13
.
8
%
)
,
subarachnoid
hemorrhage
(
10
%
)
,
recent
cerebral
infarction
(
9
%
)
,
intraparenchymatous
hemorrhage
(
8
.
14
%
)
,
hypoxic-ischemic
encephalopathy
(
3
%
)
and
other
events
such
as
Sneddon
syndrome
and
Lupus
vasculitis
.
These
findings
express
that
the
cerebrovascular
phenomena
in
this
age
group
are
unique
and
closely
related
with
the
underlying
disease
.
Diseases
Validation
Diseases presenting
"recent cerebral infarction"
symptom
sneddon syndrome
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