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Congenital candidiasis as a subject of research in medicine and human ecology.
[severe combined immunodeficiency]
Congenital
candidiasis
is
a
severe
complication
of
candidal
vulvovaginitis
.
It
occurs
in
two
forms
,
congenital
mucocutaneous
candidiasis
and
congenital
systemic
candidiasis
.
Also
newborns
are
in
age
group
the
most
vulnerable
to
invasive
candidiasis
.
Congenital
candidiasis
should
be
considered
as
an
interdisciplinary
problem
including
maternal
and
fetal
condition
(
including
antibiotic
therapy
during
pregnancy
)
,
birth
age
and
rare
genetic
predispositions
as
severe
combined
immunodeficiency
or
neutrophil-
specific
granule
deficiency
.
Environmental
factors
are
no
less
important
to
investigate
in
diagnosing
,
treatment
and
prevention
.
External
factors
(
e
.
g
.
,
food
)
and
microenvironment
of
human
organism
(
microflora
of
the
mouth
,
intestine
and
genitalia
)
are
important
for
solving
clinical
problems
connected
to
congenital
candidiasis
.
Physician
knowledge
about
microorganisms
in
a
specific
compartments
of
the
microenvironment
of
human
organism
and
in
the
course
of
defined
disorders
of
homeostasis
makes
it
easier
to
predict
the
course
of
the
disease
and
allows
the
development
of
procedures
that
can
be
extremely
helpful
in
individualized
diagnostic
and
therapeutic
process
.
