Rare Diseases Symptoms Automatic Extraction
Home
A random Abstract
Our Project
Our Team
Human spotted fever group rickettsioses are underappreciated in southern Taiwan, particularly for the species closely-related to Rickettsia felis.
[scrub typhus]
Despite
increased
identification
of
spotted
fever
group
rickettsioses
(
SFGR
)
in
animals
and
arthropods
,
human
SFGR
are
poorly
characterized
in
Taiwan
.
Patients
with
suspected
Q
fever
,
scrub
typhus
,
murine
typhus
,
leptospirosis
,
and
dengue
fever
from
April
2004
to
December
2009
were
retrospectively
investigated
for
SFGR
antibodies
(
Abs
)
.
Sera
were
screened
for
Rickettsia
rickettsii
Abs
by
indirect
immunofluorescence
antibody
assay
(
IFA
)
,
and
those
with
positive
results
were
further
examined
for
Abs
against
R
.
rickettsii
,
R
.
typhi
,
R
.
felis
,
R
.
conorii
,
and
R
.
japonica
using
micro-immunofluorescence
(
MIF
)
tests
.
Polymerase
chain
reaction
(
PCR
)
for
detection
of
SFGR
DNA
was
applied
in
those
indicated
acute
infections
.
Case
geographic
distribution
was
made
by
the
geographic
information
system
software
.
A
total
of
413
cases
with
paired
serum
,
including
90
cases
of
Q
fever
,
47
cases
of
scrub
typhus
,
12
cases
of
murine
typhus
,
6
cases
of
leptospirosis
,
3
cases
of
dengue
fever
,
and
255
cases
of
unknown
febrile
diseases
were
investigated
.
Using
IFA
tests
,
a
total
of
49
cases
with
47
(
11
.
4
%
)
and
4
(
1
.
0
%
)
cases
had
sera
potentially
positive
for
R
.
rickettsii
IgG
and
IgM
,
respectively
.
In
the
49
cases
screened
from
IFA
,
MIF
tests
revealed
that
there
were
5
cases
of
acute
infections
(
3
possible
R
.
felis
and
2
undetermined
SFGR
)
and
13
cases
of
past
infections
(
3
possible
R
.
felis
and
10
undetermined
SFGR
)
.
None
of
the
5
cases
of
acute
infection
had
detectable
SFGR
DNA
in
the
blood
specimen
by
PCR
.
Possible
acute
infection
of
R
.
felis
was
identified
in
both
one
case
of
Q
fever
and
scrub
typhus
.
The
geographic
distribution
of
SFGR
cases
is
similar
with
that
of
scrub
typhus
.
Human
SFGR
exist
and
are
neglected
diseases
in
southern
Taiwan
,
particularly
for
the
species
closely-related
to
R
.
felis
.
Diseases
Validation
Diseases presenting
"fever"
symptom
22q11.2 deletion syndrome
acute rheumatic fever
alexander disease
allergic bronchopulmonary aspergillosis
canavan disease
carcinoma of the gallbladder
child syndrome
congenital toxoplasmosis
cushing syndrome
cystinuria
dracunculiasis
erdheim-chester disease
esophageal adenocarcinoma
esophageal carcinoma
familial mediterranean fever
focal myositis
hodgkin lymphoma, classical
lamellar ichthyosis
legionellosis
locked-in syndrome
malignant atrophic papulosis
neonatal adrenoleukodystrophy
neuralgic amyotrophy
oculocutaneous albinism
papillon-lefèvre syndrome
pyomyositis
pyruvate dehydrogenase deficiency
scrub typhus
severe combined immunodeficiency
sneddon syndrome
systemic capillary leak syndrome
triple a syndrome
typhoid
waldenström macroglobulinemia
wolf-hirschhorn syndrome
This symptom has already been validated