Rare Diseases Symptoms Automatic Extraction
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Emerging scrub typhus infection in the northern region of Sri Lanka.
[scrub typhus]
There
is
an
increasing
trend
in
rickettsioses
or
typhus
fevers
in
the
island
of
Sri
Lanka
.
The
seroepidemiological
mapping
previously
published
did
not
include
the
northern
region
of
the
island
.
This
study
was
conducted
to
demonstrate
the
presence
of
scrub
typhus
(
ST
)
and
to
characterise
the
clinical
presentation
of
ST
in
this
region
.
Serum
samples
from
patients
(
n
=
64
)
with
clinical
symptoms
suspected
of
typhus
fever
following
exclusion
of
other
common
febrile
illnesses
commonly
seen
in
the
northern
region
of
Sri
Lanka
were
selected
and
screened
for
ST
using
specific
IgM
and
IgG
ELISA
(
ImBios
,
USA
)
.
ST
was
confirmed
by
serology
in
54
patients
,
with
typical
eschar
being
found
in
49
of
cases
positive
for
ST
.
Fever
was
the
sole
presenting
complaint
of
these
patients
with
the
duration
of
febrile
illness
varying
from
2
-
14
days
.
Of
these
patients
44
.
4
%
had
regional
lymphadenopathy
,
18
.
5
%
hepatomegaly
,
12
.
9
%
pneumonitis
and
9
.
3
%
splenomegaly
.
None
of
the
patients
had
a
rash
.
This
study
confirms
the
presence
of
high
numbers
of
patients
with
ST
in
northern
Sri
Lanka
.
It
was
found
that
84
.
4
%
of
the
patients
presenting
with
clinical
features
of
rickettsioses
(
54
of
the
64
)
were
seropositive
for
ST
with
a
significant
majority
having
a
typical
eschar
.
This
data
provided
will
enable
clinicians
to
be
vigilant
of
ST
in
this
region
and
provide
appropriate
therapy
and
also
facilitate
planning
for
preventive
measures
aimed
at
reducing
the
burden
of
ST
.
Diseases
Validation
Diseases presenting
"18"
symptom
acute rheumatic fever
allergic bronchopulmonary aspergillosis
scrub typhus
von hippel-lindau disease
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