Human Immunodeficiency Virus (HIV)-Negative and Human Herpes Virus-8 (HHV-8)-Positive Primary Effusion Lymphoma: A Case Report and Review of the Literature.

[primary effusion lymphoma]

Primary effusion lymphoma (PEL ) is a rare type of non-Hodgkin lymphoma that presents with serosal effusion in body cavities , without obvious tumor masses . Although PEL occurs in immunocompromised patients that are human immunodeficiency virus (HIV ) positive , it also occurs in immunocompetent human herpes virus-8 (HHV-8 )-positive patients . Herein we present an immunocompetent , HIV-negative , CD-20 -negative , HHV-8 -positive patient with pleural effusion that was diagnosed as PEL . The CHOP protocol and talc pleurodesis were administered . HHV-8 plays a causative role in PEL and is important for differentiating PEL from other types of lymphoma . As such , in addition to pleurodesis antiviral treatment should be considered for optimal treatment outcome .None declared .

Diseases
Validation

Diseases presenting "immunodeficiency" symptom

adrenal incidentaloma

allergic bronchopulmonary aspergillosis

cushing syndrome

dracunculiasis

hirschsprung disease

hodgkin lymphoma, classical

homocystinuria without methylmalonic aciduria

kabuki syndrome

legionellosis

malignant atrophic papulosis

oculocutaneous albinism

omenn syndrome

papillon-lefèvre syndrome

primary effusion lymphoma

primary hyperoxaluria type 1

pyomyositis

severe combined immunodeficiency

sneddon syndrome

werner syndrome

wiskott-aldrich syndrome

wolf-hirschhorn syndrome

x-linked adrenoleukodystrophy

This symptom has already been validated