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Primary pleomorphic liposarcoma of the orbit: a case report.
[pleomorphic liposarcoma]
To
our
knowledge
,
pleomorphic
liposarcoma
(
PL
)
of
the
orbit
has
only
been
reported
in
the
literature
four
times
.
This
rarity
makes
it
more
difficult
to
diagnose
and
to
treat
in
this
clinical
setting
.
A
62
-
year
-old
female
presented
with
pruritus
,
edema
,
proptosis
and
diplopia
5
months
OS
.
Imaging
revealed
an
intraorbital
mass
displacing
the
globe
,
with
infiltration
into
the
sinus
.
The
tumor
was
removed
and
the
histological
examination
revealed
a
highly
cellular
tumor
with
heterogenous
histology
,
with
a
few
vacuolated
cells
and
many
malignant
features
.
Immunohistochemistry
allowed
for
the
differential
diagnosis
,
resulting
in
a
diagnosis
of
PL
of
the
orbit
.
The
cells
were
immuno-
positive
for
S-
100
and
negative
for
all
other
relevant
markers
.
According
to
the
literature
,
prognosis
for
this
neoplasm
is
quite
poor
,
and
exenteration
represents
the
best
treatment
option
.
The
patient
refused
exenteration
and
radiation
therapy
,
however
,
at
2
year
follow-up
,
she
remained
recurrence-free
.
Diseases
Validation
Diseases presenting
"diplopia 5 months os"
symptom
pleomorphic liposarcoma
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