Epidemiology of hemoglobinopathies and thalassemias in individuals referred to the haematology research centre, Shiraz University of Medical Sciences, Shiraz, Iran from 2006 to 2011.

[alpha-thalassemia]

Hemoglobinopathies and thalassemias are the most frequent genetic hereditary disorders with an increasing global health burden , especially in low - and middle -income countries . We aimed to determine the epidemiologic pattern of hemoglobinopathies and thalassemias in individuals referred to the Haematology Research Centre , Shiraz University of Medical Sciences , Shiraz , Iran , which is the most important referral center in Southern Iran during 2006 to 2011 . The most frequent abnormality was β-thalassemia (β-thal ) minor (24 .0 %), followed by α-thalassemia (α-thal ) trait (10 .0 %), hemoglobin (Hb ) S trait (4 .0 %) and Hb D-Punjab trait (4 .0 %). Because this center is a referral center , we detected a higher prevalence compared to the normal population ; however , these data could help policymakers and health service providers to better programming for prevention of births affected with Hb disorders .

Diseases
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Diseases presenting "frequent genetic hereditary disorders" symptom

alpha-thalassemia

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