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Long-term results after treatment of periodontitis in patients with Papillon-Lefèvre syndrome: success and failure.
[papillon-lefèvre syndrome]
Retrospective
evaluation
of
periodontal
status
in
patients
with
Papillon-
Lefèvre
syndrome
(
PLS
)
observed
for
≥
10
years
;
identification
of
factors
that
may
influence
treatment
outcome
;
and
reporting
of
the
outcome
of
dental
implants
in
four
PLS
patients
.
All
PLS
patients
currently
registered
at
the
Department
of
Periodontology
,
Goethe-
University
Frankfurt
with
a
follow-up
≥
10
years
(
13
-
33
years
;
mean
22
years
)
were
recruited
.
Eight
patients
(
aged
17
-
46
years
)
from
five
families
(
three
pairs
of
siblings
)
were
included
.
After
comprehensive
periodontal
therapy
in
eight
PLS
patients
,
teeth
were
retained
in
only
two
.
In
six
patients
,
all
teeth
were
extracted
,
almost
entirely
due
to
periodontal
reasons
.
In
four
patients
,
teeth
were
prosthodontically
restored
with
implants
.
Currently
,
three
patients
already
show
peri-implantitis
.
In
some
PLS
patients
,
periodontitis
may
be
arrested
by
:
combined
mechanical
and
antibiotic
periodontal
treatment
;
extraction
of
severely
diseased
teeth
;
oral
hygiene
instructions
;
intensive
maintenance
therapy
;
and
microbiological
monitoring
and
treatment
of
the
infection
with
Aggregatibacter
actinomycetemcomitans
.
Implants
in
PLS
patients
who
did
not
follow
any
maintenance
programme
have
a
high
risk
of
peri-implantitis
and
implant
loss
.
Treatment
of
PLS
patients
has
always
to
be
considered
as
high
-risk
cases
.
