Papillon Lefevre Syndrome and footsteps of mycobacterium tuberculosis.

[papillon-lefèvre syndrome]

Papillon Lefevre Syndrome ( PLS ) is a very rare genetic syndrome that only less than 500 cases have reported in the world . Patients have a typical cutaneous involvement with hyperkeratosis especially on the soles and palms and early shedding of primary teeth . Internal organs involvement such as liver abscess has been presented as case reports . This is for the first time that a genetically documented PLS with footsteps of mycobacterium tuberculosis in liver and kidney will report .