Rare Diseases Symptoms Automatic Extraction

Palmoplantar keratoderma with progressive gingivitis and recurrent pyodermas.

[papillon-lefèvre syndrome]

Papillon-Lefèvre syndrome (PLS) is a rare inherited palmoplantar keratoderma (PPK) that is associated with progressive gingivitis and recurrent pyodermas. We present a case exhibiting classic features of this autosomal-recessive condition and review the current understanding of its pathophysiology, diagnosis, and treatment. Additionally, a review of pertinent transgredient PPKs is undertaken, with key and distinguishing features of each syndrome highlighted.

Diseases presenting "palmoplantar keratoderma" symptom

  • epidermolysis bullosa simplex
  • erythropoietic protoporphyria
  • kindler syndrome
  • papillon-lefèvre syndrome

This symptom has already been validated