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Potentially malignant disorders of the oral cavity: a clinical study.
[oral submucous fibrosis]
Oral
cancers
in
India
,
unlike
in
the
West
are
the
most
common
cancers
encountered
,
be
it
a
primary
or
a
tertiary
referral
practice
.
This
makes
the
study
and
management
of
these
cancers
an
important
issue
especially
for
the
otolaryngologist
.
It
is
well
known
that
the
most
common
variant
of
oral
cancers
is
the
squamous
cell
carcinoma
.
Also
the
etiology
is
well
established
;
with
tobacco
use
in
both
smoking
and
smokeless
forms
,
alcohol
,
betel
nut
and
recently
the
Human
Papilloma
virus
infection
being
implicated
.
Certain
conditions
which
definitely
increase
the
probability
of
getting
oral
cancers
are
known
and
this
study
aims
in
revisiting
these
aspects
of
pre-malignancy
.
The
progression
from
a
pre-cancerous
lesion
/
condition
to
frank
cancer
is
well
established
across
many
studies
and
many
specialties
.
Also
timely
recognizing
these
pre-cancerous
conditions
and
administration
of
proper
treatment
will
greatly
help
in
reducing
the
morbidity
and
mortality
from
subsequent
much
advanced
and
dangerous
oral
cancer
.
Keeping
these
facts
in
mind
this
study
was
planned
to
study
the
established
pre-cancerous
lesions
which
are
known
to
progress
to
oral
cancers
.
Diseases
Validation
Diseases presenting
"cancer"
symptom
achondroplasia
acute rheumatic fever
adrenal incidentaloma
alpha-thalassemia
benign recurrent intrahepatic cholestasis
cadasil
canavan disease
carcinoma of the gallbladder
cholangiocarcinoma
coats disease
congenital adrenal hyperplasia
congenital diaphragmatic hernia
cowden syndrome
cushing syndrome
cutaneous mastocytosis
dedifferentiated liposarcoma
dystrophic epidermolysis bullosa
epidermolysis bullosa simplex
erdheim-chester disease
erythropoietic protoporphyria
esophageal adenocarcinoma
esophageal carcinoma
esophageal squamous cell carcinoma
familial hypocalciuric hypercalcemia
familial mediterranean fever
gm1 gangliosidosis
heparin-induced thrombocytopenia
hereditary cerebral hemorrhage with amyloidosis
hirschsprung disease
hodgkin lymphoma, classical
inclusion body myositis
junctional epidermolysis bullosa
kabuki syndrome
kallmann syndrome
kindler syndrome
lamellar ichthyosis
liposarcoma
locked-in syndrome
lymphangioleiomyomatosis
monosomy 21
neuralgic amyotrophy
oculocutaneous albinism
oligodontia
oral submucous fibrosis
papillon-lefèvre syndrome
pendred syndrome
pleomorphic liposarcoma
primary effusion lymphoma
proteus syndrome
pyomyositis
pyruvate dehydrogenase deficiency
severe combined immunodeficiency
sneddon syndrome
systemic capillary leak syndrome
triple a syndrome
von hippel-lindau disease
waldenström macroglobulinemia
well-differentiated liposarcoma
werner syndrome
wiskott-aldrich syndrome
wolf-hirschhorn syndrome
x-linked adrenoleukodystrophy
This symptom has already been validated