Rare Diseases Symptoms Automatic Extraction

Omenn syndrome: therapeutic effects of cyclosporin.

[omenn syndrome]

Omenn syndrome is a severe combined immunodeficiency with features of generalised erythroderma alopecia and evidence of Th2 inflammation (eosinophilia and raised IgE). We describe a differential effect of 2 calcineurin inhibitors, cyclosporine A (CsA) and tacrolimus, with CsA rapidly improving the erythroderma and lymphocytosis but tacrolimus having little effect.

Diseases presenting "alopecia" symptom

  • cadasil
  • congenital adrenal hyperplasia
  • cutaneous mastocytosis
  • epidermolysis bullosa simplex
  • harlequin ichthyosis
  • junctional epidermolysis bullosa
  • lamellar ichthyosis
  • oligodontia
  • omenn syndrome
  • pleomorphic liposarcoma
  • proteus syndrome
  • werner syndrome

This symptom has already been validated