Rare Diseases Symptoms Automatic Extraction

Omenn syndrome: therapeutic effects of cyclosporin.

[omenn syndrome]

Omenn syndrome is a severe combined immunodeficiency with features of generalised erythroderma alopecia and evidence of Th2 inflammation (eosinophilia and raised IgE). We describe a differential effect of 2 calcineurin inhibitors, cyclosporine A (CsA) and tacrolimus, with CsA rapidly improving the erythroderma and lymphocytosis but tacrolimus having little effect.

Diseases presenting "severe combined immunodeficiency" symptom

  • achondroplasia
  • alpha-thalassemia
  • child syndrome
  • cholangiocarcinoma
  • junctional epidermolysis bullosa
  • krabbe disease
  • omenn syndrome
  • severe combined immunodeficiency
  • wiskott-aldrich syndrome

This symptom has already been validated