[A case of neuralgic amyotrophy with antiganglioside antibody].

[neuralgic amyotrophy]

A 54 -year -old-man experienced pain from his left shoulder to his left arm and had difficulty in lifting his arm after a febrile episode . Three weeks after the onset , he was admitted to our hospital . Neurological examination demonstrated weakness and atrophy of the left deltoid muscle . Deep tendon reflexes were normal and no pathological reflexes were elicited . CSF total protein was slightly increased . The occurrence rate of F-waves was decreased in the left upper limb . Magnetic resonance imaging (MRI ) study of the cervical cord and brachial plexus with and without Gadolinium infusion showed no abnormalities . Serological study showed that IgM anticytomegalovirus antibody was positive , and that serum IgM anti-GalNAc-GD 1 a antibody and IgM anti-GM 2 antibody were positive . Symptoms were improved after treatment with mecobalamin , 1 .5 mg /day . This case was considered neuralgic amyotrophy after cytomegalovirus infection . The antiganglioside antibodies may play some role in its pathogenesis .