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Four cases of anti-ganglioside antibody-positive neuralgic amyotrophy with good response to intravenous immunoglobulin infusion therapy.
[neuralgic amyotrophy]
Neuralgic
amyotrophy
(
NA
)
,
which
is
an
idiopathic
disorder
in
the
peripheral
nerves
,
is
characterized
by
an
acute
onset
of
unilateral
pain
in
the
proximal
limbs
followed
by
muscular
weakness
and
wasting
.
Some
cases
of
NA
are
thought
to
be
related
to
immune
pathogenic
disorders
such
as
Guillain-
Barré
syndrome
(
GBS
)
.
We
report
the
case
of
four
patients
with
NA
who
were
positive
for
anti-
N-
acetylgalactosaminyl
GD
1
a
(
anti-
GalNAc-GD
1
a
)
antibodies
,
had
a
preceding
infection
,
and
showed
a
good
response
to
intravenous
immunoglobulin
infusion
therapy
.
Anti-ganglioside
antibodies
,
especially
the
anti-
GalNAc-GD
1
a
antibody
,
may
be
a
useful
marker
for
predicting
response
to
immune
therapy
.
Diseases
Validation
Diseases presenting
"is characterized by an acute onset of unilateral pain in the proximal limbs followed by muscular weakness and wasting"
symptom
neuralgic amyotrophy
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