Challenging pain syndromes: Parsonage-Turner syndrome.

[neuralgic amyotrophy]

Parsonage-Turner syndrome (PTS ) is a rare disorder typically characterized by an abrupt onset of upper extremity pain followed by progressive neurologic deficits , including weakness , atrophy , and occasionally sensory abnormalities . The exact cause and pathophysiology of PTS are complex and incompletely understood . Autoimmune , genetic , infectious , and mechanical processes have all been implicated . No specific treatments have been proven to reduce neurologic impairment or improve the prognosis of PTS . Most patients with PTS are treated with a multidisciplinary approach that includes both physical therapy and pharmacologic treatment , often with multiple agents . Further research is needed .